In 2013, the Federal Aviation Administration and Volpe National Transportation System Center conducted a series of acoustic measurements with a propeller driven aircraft operating in the regions near Houston, Texas. The recorded data on octave band sound levels, aircraft locations, temperature and wind speed profiles were used in the current study to quantify the uncertainties for predicting the propagation effects of aircraft noise. Use of the Aviation Environmental Design Tool (AEDT) was explored for its accuracy and validity in real world scenarios offered by the dataset. The sound exposure level (SEL) data for each section of a flight path was used instead of the time history data for reducing the directivity effect of the sound source due to the change in its relative positions with the receivers. A subtraction-based method was introduced to analyze the propagation effect in which the SELs between two receiver locations were compared. The use of the subtraction method reduces the possible influences of the sound power variations along the flight paths. The measured data for a spiral and a level flight event were presented and the AEDT predictions on the propagation effects were examined in this paper.